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Treatment and Outcomes of Fungal Prosthetic Joint Infections: A Systematic Review of 225 Cases

Authors/contributors
Publication
The Journal of Arthroplasty
Date
5/2023
Notes

Key Question

The key question addressed in this paper is: What are the treatment outcomes for fungal prosthetic joint infections (PJIs) after total joint arthroplasty?

Findings

  • Fungal prosthetic joint infections (PJIs) are rare but severe.
  • Unlike bacterial PJIs, there is no clear consensus on the optimal management of fungal PJIs.
  • The paper systematically reviews 225 cases to provide insights into treatment and outcomes.

Clinical Implications

  • Understanding the treatment outcomes for fungal PJIs can help clinicians make more informed decisions on how to manage these rare but severe infections.
  • The paper highlights the need for a standard treatment protocol for fungal PJIs, which currently does not exist.

Strengths

  1. Systematic Review: The paper is a systematic review, which is a high level of evidence.
  2. Large Sample Size: Includes 225 cases, which enhances the reliability of the findings.
  3. Comprehensive Search: The authors used PubMed and Embase databases for their literature search, which are reputable sources.

Limitations

  1. Observational Data: The paper is based on observational studies, which inherently have limitations compared to randomized controlled trials.
  2. Lack of Standardization: As the paper reviews multiple studies, there may be a lack of standardization in treatment protocols among the reviewed cases.
  3. Limited to Published Literature: The systematic review is based on published literature, which may have publication bias.
Citation
1.
Gonzalez MR, Bedi ADS, Karczewski D, Lozano-Calderon SA. Treatment and Outcomes of Fungal Prosthetic Joint Infections: A Systematic Review of 225 Cases. The Journal of Arthroplasty. Published online 2023:S0883540323004643.